Track Categories
The track category is the heading under which your abstract will be reviewed and later published in the conference printed matters if accepted. During the submission process, you will be asked to select one track category for your abstract.
In the modern scientific world, the process of drug discovery is quite complex. Drug discovery is a lengthy process and it is expensive. Its main application includes target identification and investigations into the mechanism of drug discovery and toxicity and the goal of biomarkers. In structural proteomics, it determines their functions, structures and their three-dimensional structure of proteins. The chemical proteomics is used to identify the protein binding partners and the cellular targets and used to design small molecules, investigate and understand the protein function. The pharmacoproteomics is used to observe the alternation of proteins on an act of drug administration. The computational design sparks the drug interactions.
The advancements in cancer proteomics have developed through various technologies. Cancer classes in the alternation in which the oncogenic mutation had been identified and protein domains are enclosed by the cancer genes. Commonly genes are altered by chromosomal alternation. The important role in the gene expression has been involved in the cell division cycle, apoptosis, and cell migration. Hereditary is also considered as the biggest risk for prostate cancer that intense clinical importance. The tumor is the new growth of abnormal tissue. It cannot be controlled and it is progressive.
Protein microarray is one of the technology and it is a critical tool in biochemistry and molecular biology. The analytical microarray is the most powerful multiplexed detection technology. The functional microarray is one of the important tools for a high-throughput and large-scale system for biological studies. Some application of functional microarray is the detection of protein binding properties as protein-protein interaction, protein -DNA interaction, protein-RNA interaction, an antigen-antibody interaction. There are numerous cellular processes in which protein kinases are involved. Recording and analyzing of immune responses.
Translational Proteomics covers all territories of human proteomics utilizing multi-disciplinary ways to deal with unwind complex infection forms. It centers around the quick scattering of novel disclosures. Proteins are essential parts of living beings, as they are the principal segments of the physiological metabolic pathways of cells. The reason for most human malady lies in the utilitarian dysregulation of protein communications. Proteomics, which incorporates the investigation of cell protein collaborations, has developed from propels in logical information and innovation.
Next-generation sequencing is a high through-put methodology that empowers the sequencing of the base pairs in DNA or RNA samples and it also permits the future of personalized medicine. The targeted next-generation DNA sequencing reactions and suitable point of mutation detection examine in the preserved tumor samples can be imagined by mobile phone microscopy. Exome sequencing is a genomic technique for sequencing all the protein sequencing genes. Agrigenomic technology is used to transform the traditional approaches for monitoring and it includes microarrays for genotyping, for next-generation sequencing and polymerase chain reaction.
In proteomics, the mass gives the information on the protein identity, its chemical modifications, and its structures. Tandem mass spectrometry contains multiple steps of mass spectrometry selections with some pattern of fragmentation arise in between the stages. Gas chromatography is used to analyze the volatile compounds and helps to the different substances within the test samples. Pharmacokinetics helps the prescribers adjust the drug more accurately and its application is to individualize the therapeutic drug monitoring. It is a drug depends on patient-related factors and also on the drugs chemical properties.
The mass spectrometer is a qualitative analytical technique and it is now in the front line of the protein centered research. The strategics and the problems of the methods are in use for the quantitative analysis of peptides and proteins and finally, it was proteomes by the mass spectrometer. Protein turns over in living systems has been measured with the stable isotope labeled tracers for over half a century. Neuroproteomics has a role in the clarification of disease mechanisms and it is a powerful tool for the identification of biomarkers. The targeted proteomics assures the advance of our understanding of biological networks and the phenotypic significance of specific network state and to the advance of biomarkers into clinical use or chemical studies.
Structural bioinformatics is the branch of bioinformatics which is identified with the examination and expectation of the three-dimensional structure of natural macromolecules, for example, proteins, RNA, and DNA. It manages speculations about macromolecular 3D structure.
The proteins have accelerated the development of very powerful methods in protein analysis. The progression of clinical proteomics adds the constraint with the regards to the in vitro diagnostic application. It discovers the programs to be led in the selection of putative new biomarkers of the human pathogens. Enzymes markers are specialized in the protein complex that assists the chemical changes in every part of the body and the marker protein enhance across the cell membrane and serve to identify the cell. Lipoprotein has been the risk factor for cardiovascular diseases, all the lipoprotein carry cholesterol but exalted by the levels of lipoprotein other than high-density lipoprotein and associated with an increased risk factor of coronary heart diseases.
The Human Proteome Map is the doorway for the interactive resource to the scientific community by consolidating the massive peptide sequencing the result from the draft map to the human proteome project. Isolating a subset of cells from tissues requires mechanical and biochemical sorting and it is a process to amend the cellular signaling and also the composition of proteomics. Medically it is necessary to secrete the proteins which include cytokines, the coagulation factor, growth factors, and other signaling molecules. A large number of genes with varied normal functions are complexed in human cancer. Certain proteins show distinct expression between different forms of cancer, considering the other protein show variable expression within the different states.
Personalized medication guarantees to change the conveyance of medicinal services to patients. Human services will develop from a responsive "one-measure fits-all" framework towards an arrangement of prescient, preventive, and exactness mind. It won't just spotlight on the distinguishing proof of biomarkers and hereditary marks for avoidance and forecast of restorative reaction yet will likewise improve mindfulness about way of life and preventive way of life changes.
Docking offers tools for fundamental studies of protein interactions and affords a structural basis for drug design. The in-silico study in medicine is a reflection to have the potential speed the rate of discovery while compressing the need for expensive lab work and clinical trials. Structure-Based Drug Design depends on the knowledge of the three-dimensional structure of the biological target. computer-aided drug design and the delivery system offers a detailed discussion of the computer-assisted techniques is used to discover, design, effective and safe drugs.
Bioinformatics is the study of biology through computer modeling and analysis. It is a multi-discipline research involving biology, statistics, data-mining, machine learning, and algorithms. An algorithm is a set of rules used to solve a problem, especially by the computer.
Food intake is essentially important for every life on earth to sustain the physical as well as mental functions. The outcome of food intake will be manifested in the health state and its dysfunction. The molecular information about the protein expression change caused by diets will assist us to understand the significance of functional foods. Nutritional proteomics promotes a new area in functional food studies for a better understanding of the role of functional foods in health and disease.
The investigation of nucleic acids started with the disclosure of DNA, advanced to the investigation of qualities and little parts, and has now detonated to the field of genomics. Genomics is the investigation of whole genomes, including the total arrangement of qualities, their nucleotide succession, and association, and their cooperation’s inside an animal category and with different species. The advances in genomics have been made conceivable by DNA sequencing innovation.
Proteomics is a field with developing enthusiasm for relatively every everyday issue science. In horticulture, creature and veterinary research, nonetheless, utilization of proteomics is yet constrained, notwithstanding the huge number of potential applications. Accordingly, there is a squeezing requirement for more extensive utilize and spread of proteomics in creature and veterinary sciences. Plant Proteomics is a fundamental source of information about biological systems and it generates knowledge about interactions, functions and catalytic activity of proteins and the structural and functional determinants of cells.
Molecular medicine is the biological mechanism of diseases at the cellular and molecular levels for enhancing the diagnosis, treatment, and prevention of diseases. The main objectives are identifying all proteins, analyze differential protein expression by using different samples and it understands the protein interaction networks. Cellular medicine defines the daily intake of specific micronutrients as a preventative measure for maintaining health and safe of control of many pathological conditions.
Environmental proteomics is the investigation of the articulation profile of proteins separated straightforwardly from living beings and some balanced out extracellular proteins present in ecological examples is a creating branch of soil science since the fundamental papers seemed twenty years back.
DNA profiling is used in forensic techniques and it determines the process of individual DNA characteristics. Restriction Fragment Length Polymorphism analysis is used to identify genetics used in DNA profiling. Polymerase chain reaction analysis requires a DNA template that contains the DNA target region to amplify. Short Tandem Repeat assay is in the power of discrimination and also used for forensic testing.Y-chromosome analysis is used to research in the paternal line. The mitochondrial analysis is used in the forensic field and also to create DNA profiles from other DNA analysis.
Systems Biology involves developing the understanding of a biological system through mathematical and computational modeling of the interactions of components of the system, leading to the expression of this understanding in qualitative and quantitative terms. It is concerned with the study of biological functions and mechanisms, underpinning inter and intra-cellular dynamical networks, by means of signal and system-oriented approaches. It is a biology-based study that focuses on the systematic study of interactions in biological systems and to discover new emergent properties.